Nicolas von Ahsen Selected Research

Thiopurine S methyltranferase deficiency

10/2012	Establishment of thiopurine S-methyltransferase gene knockdown in jurkat T-lymphocytes: an in vitro model of TPMT polymorphism.
12/2005	Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study.

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Nicolas von Ahsen Research Topics

Disease

6	Neoplasms (Cancer) 01/2019 - 06/2006
4	Alzheimer Disease (Alzheimer's Disease) 10/2014 - 01/2006
3	Dementia (Dementias) 01/2011 - 01/2006
3	Cognitive Dysfunction 01/2009 - 11/2005
3	Drug-Related Side Effects and Adverse Reactions 02/2007 - 12/2005
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2015 - 12/2005
2	Multiple Sclerosis 12/2012 - 01/2006
2	Thiopurine S methyltranferase deficiency 10/2012 - 12/2005
2	Autoimmune Diseases (Autoimmune Disease) 01/2012 - 04/2004
2	Colorectal Neoplasms (Colorectal Cancer) 03/2008 - 11/2007
2	Crohn Disease (Crohn's Disease) 07/2007 - 12/2005
1	Prostatic Neoplasms (Prostate Cancer) 01/2019
1	Shock 02/2014
1	Anemia 06/2013
1	Epstein-Barr Virus Infections 12/2012
1	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 01/2011
1	Acquired CJD 01/2011
1	Depressive Disorder (Melancholia) 01/2009
1	Prion Diseases (Transmissible Spongiform Encephalopathies) 01/2008
1	Seizures (Absence Seizure) 11/2007
1	Alcohol Withdrawal Seizures 11/2007
1	Coronary Disease (Coronary Heart Disease) 07/2007
1	Venous Thrombosis (Deep-Vein Thrombosis) 07/2007
1	Male Infertility (Male Sterility) 06/2006
1	Cardiovascular Diseases (Cardiovascular Disease) 06/2006
1	Neurodegenerative Diseases (Neurodegenerative Disease) 06/2006
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2006
1	Brain Concussion (Cerebral Concussion) 01/2006
1	Relapsing-Remitting Multiple Sclerosis 01/2006
1	Parkinson Disease (Parkinson's Disease) 01/2006
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2006
1	Leukopenia 01/2006
1	Alcoholism (Alcohol Abuse) 11/2005
1	Atrophy 11/2005
1	Hypoxia (Hypoxemia) 04/2005
1	Balkan Nephropathy (Balkan Endemic Nephropathy) 03/2005
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 04/2004
1	Thrombosis (Thrombus) 01/2004
1	Thrombophilia 01/2004

Drug/Important Bio-Agent (IBA)

5	Apolipoproteins E (ApoE)IBA 10/2014 - 11/2007
5	Azathioprine (Imuran)FDA LinkGeneric 07/2007 - 04/2004
3	DNA (Deoxyribonucleic Acid)IBA 02/2014 - 11/2007
3	2-mercaptopurineIBA 10/2012 - 04/2004
3	ApolipoproteinsIBA 01/2011 - 01/2006
2	Interleukin-8 (Interleukin 8)IBA 10/2014 - 01/2012
2	Biomarkers (Surrogate Marker)IBA 02/2014 - 01/2011
2	tau Proteins (tau Protein)IBA 01/2011 - 01/2006
2	Apolipoprotein E2IBA 01/2009 - 11/2007
2	Apolipoprotein E4IBA 11/2007 - 11/2005
2	EnzymesIBA 02/2007 - 01/2006
2	Inosine TriphosphataseIBA 02/2007 - 12/2005
1	IsoenzymesIBA 01/2019
1	Immunosuppressive Agents (Immunosuppressants)IBA 01/2015
1	Thioacetamide (Thioacetamid)IBA 02/2014
1	hydrogen sulfite (bisulfite)IBA 02/2014
1	Hemoglobins (Hemoglobin)IBA 06/2013
1	Vitamin D FDA LinkGeneric 12/2012
1	Amyloid (Amyloid Fibrils)IBA 01/2011
1	S100 Proteins (S 100 Protein)IBA 01/2011
1	Phosphopyruvate Hydratase (Enolase)IBA 01/2011
1	14-3-3 Proteins (14-3-3 Protein)IBA 01/2011
1	XenobioticsIBA 03/2008
1	Cytochrome P-450 CYP3AIBA 11/2007
1	Apolipoprotein E3IBA 11/2007
1	6-thioguanylic acidIBA 07/2007
1	Folic Acid (Vitamin M)FDA LinkGeneric 07/2007
1	Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA 07/2007
1	AntioxidantsIBA 06/2006
1	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2006
1	InterferonsIBA 01/2006
1	Proteins (Proteins, Gene)FDA Link 01/2006
1	Creatine Kinase (Creatine Phosphokinase)IBA 01/2006
1	Protein Isoforms (Isoforms)IBA 01/2006
1	thiopurine methyltransferase (thiopurine S-methyltransferase)IBA 12/2005
1	Estrogens (Estrogen)FDA Link 04/2005
1	Estrogen Receptor betaIBA 04/2005
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 03/2005
1	Thioguanine (Tioguanine)FDA Link 04/2004
1	Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric 04/2004
1	Prothrombin (Factor II)IBA 01/2004

Therapy/Procedure

4	Therapeutics 10/2012 - 12/2005
1	Castration 01/2019
1	Immunotherapy 01/2012
1	Organ Transplantation 04/2004